| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Top Quality Nootropics 4-DMA-7, 8-Dhf Powder CAS 1205548-00-0
| Product Name | 4'-DiMethylaMino 7,8-Dihydroxyflavone HydrobroMide |
| CasNo | 1205548-00-0 |
| Content | 98% |
| Appearance | Yellow powder |
| Apply | Apply |
| Capacity | 100kgs per month |
| Source | synthetic |
| Place of Origin | China Yinherb-Lab |
| Packing | 1kg/ bag,25kg/ Drum,As per clien's requirements. |
| Minimum Order Quantity | 1kg |
| Storage | Kept in dry, cool, and shaded place with original packaging, avoid moisture, store at room temperature. |
Product introduction
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
7,8-DHF is both orally bioavailable and able to penetrate the blood-brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer's disease.
7,8-DHF has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer's disease, cognitive deficits in schizophrenia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome.
7,8-DHF also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents.
In addition, 7,8-DHF possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.
| Name | CAS No. | Purity |
| Magnesium Taurate | 334824-43-0 | 98.0% |
| Galantamine Hydrobromide | 69353-21-5 | 98.0% |
| Tianeptine | 66981-73-5 | 99.0% |
| Tianeptine sodium | 30123-17-2 | 99.0% |
| Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
| 9-ME-BC(9-Methyl-9H-beta-carboline) | 2521/7/5 | 99.0% |
| Agomelatine | 138112-76-2 | 99.0% |
| 6-Paradol 98% | 27113-22-0 | 98% Oil form |
| 6-Paradol 50% | 27113-22-0 | 50% Powder form |
| Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
| Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 98.0% |
| β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 98.0% |
| Noopept,GVS-111 | 157115-85-0 | 99.0% |
| Piracetam | 7491-74-9 | 99.0% |
| Phenibut | 1078-21-3 | 99.0% |
| Coluracetam | 135463-81-9 | 99.0% |
| N-Methyl-D-aspartic acid(NMDA) | 6384-92-5 | 99.0% |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99% Powder form |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50% Graininess form |
| Citicoline | 987-78-0 | 99.0% |
| PRL-8-53 | 51352-87-5 | 98.0% |
| NSI-189 Phosphate | 1270138-41-4 | 99.0% |
| Phenylpiracetam hydrazide | 77472-71-0 | 99.0% |
| N-Acetyl-L-cysteine ethyl ester | 59587-09-6 | 98.0% |
| 1-(1-Adamantylcarbonyl) proline | 35084-48-1 | 98.0% |
| 7,8-Dihydroxyflavone | 38183-03-8 | 98% |
| YK-11 | 431579-34-9 | 99.0% |
| TLB-150 | 1208070-53-4 | 99.0% |
| OTR-AC | 99.0% | |
| 5a-hydroxy laxogenin | 56786-63-1 | 99.0% |
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