Yinherb Lab J-147 Bulk Raw Powder 99% Purity
Product Name:2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide
Other Name:J-147, J147
CAS:1146963-51-0
MF:C18H17F3N2O2
Appearance: White Fine Powder
Capacity: 10kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
What is J-147?
J147 was discovered based upon efficacy in multiple cell culture models of age-associated pathologies rather than exclusively amyloid metabolism.
It is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice.
The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques, etc.
J-147 Benefits
J-147 is a novel neurotrophic drug for cognitive enhancement and alzheimer's disease. J-147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in alzheimer's disease (ad) transgenic mice. the neurotrophic and memory-enhancing activities of J-147 are associated with an increase in brain derived neurotrophic factor (bdnf) levels and the expression of bdnf responsive proteins, the enhancement of ltp, the preservation of synaptic protein, the reduction of amyloid plaques.
J-147 Mode of Action
The J147 drug is also reported to address other biological aging factors, such as preventing the leakage of blood from microvessels in mice brains. The development of J147 follows the chemical pharmacological way, contrary to biological ways that exploit e.g. use of bacteriophages.
Enhanced neurogenic activity over J147 in human neural precursor cells has its derivative called CAD-31. CAD-31 is enhancing the use of free fatty acids for energy production by shifting of the metabolic profile of fatty acids toward the production of ketone bodies, a potent source of energy in the brain when glucose levels are low.
The target molecule is a protein called ATP synthase, which is found in the mitochondria.
1.Improving Memory
2.Improving the brain function
3.Preventing and treating senile dementia
4.Enhancing the learning ability
5.Increasing the attention
6.Relieving the anxiety
J-147 HPLC &NMR Test report by Yinherb
| Name |
CAS No. |
Purity |
| Magnesium Taurate |
334824-43-0 |
98.0% |
| Galantamine Hydrobromide |
69353-21-5 |
98.0% |
| Tianeptine |
66981-73-5 |
99.0% |
| Tianeptine sodium |
30123-17-2 |
99.0% |
| Tianeptine hemisulfate monohydrate (THM) |
1224690-84-9 |
99.0% |
| 9-ME-BC(9-Methyl-9H-beta-carboline) |
2521/7/5 |
99.0% |
| Agomelatine |
138112-76-2 |
99.0% |
| 6-Paradol 98% |
27113-22-0 |
98% Oil form |
| 6-Paradol 50% |
27113-22-0 |
50% Powder form |
| Nicotinamide Riboside Chloride(NRC) |
23111-00-4 |
98.0% |
| Beta-Nicotinamide Mononucleotide(NMN) |
1094-61-7 |
98.0% |
| β-Nicotinamide Adenine Dinucleotide(NAD+) |
53-84-9 |
98.0% |
| Noopept,GVS-111 |
157115-85-0 |
99.0% |
| Piracetam |
7491-74-9 |
99.0% |
| Phenibut |
1078-21-3 |
99.0% |
| Coluracetam |
135463-81-9 |
99.0% |
| N-Methyl-D-aspartic acid(NMDA) |
6384-92-5 |
99.0% |
| Alpha GPC(Choline Alfoscerate) |
28319-77-9 |
99% Powder form |
| Alpha GPC(Choline Alfoscerate) |
28319-77-9 |
50% Graininess form |
| Citicoline |
987-78-0 |
99.0% |
| PRL-8-53 |
51352-87-5 |
98.0% |
| NSI-189 Phosphate |
1270138-41-4 |
99.0% |
| Fonturace.tam hydrazide |
77472-71-0 |
99.0% |
| N-Acetyl-L-cysteine ethyl ester |
59587-09-6 |
98.0% |
| 1-(1-Adamantylcarbonyl) proline |
35084-48-1 |
98.0% |
| |
|
|
| TLB-150 |
1208070-53-4 |
99.0% |
| OTR-AC |
|
99.0% |
| 5a-hydroxy laxogenin |
56786-63-1 |
99.0% |
Q1: Can i get some samples
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow
Q3: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What's your MOQ
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount
A:Different quantity has different discount.
Q7: How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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